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Page 1
Role of Nuclear NAD+ in Retinal Homeostasis.
Adv Exp Med Biol. 2023;1415:235-239. doi: 10.1007/978-3-031-27681-1_34.
Adv Exp Med Biol. 2023.
PMID: 37440039
Review.
Reduced nuclear NAD+ drives DNA damage and subsequent immune activation in the retina.
Brown EE, Scandura MJ, Mehrotra S, Wang Y, Du J, Pierce EA.
Brown EE, et al. Among authors: scandura mj.
Hum Mol Genet. 2022 May 4;31(9):1370-1388. doi: 10.1093/hmg/ddab324.
Hum Mol Genet. 2022.
PMID: 34750622
Free PMC article.
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Expression of NMNAT1 in the photoreceptors is sufficient to prevent NMNAT1-associated retinal degeneration.
Brown EE, Scandura MJ, Pierce EA.
Brown EE, et al. Among authors: scandura mj.
Mol Ther Methods Clin Dev. 2023 Apr 18;29:319-328. doi: 10.1016/j.omtm.2023.04.003. eCollection 2023 Jun 8.
Mol Ther Methods Clin Dev. 2023.
PMID: 37214313
Free PMC article.
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Gene Therapy Preserves Retinal Structure and Function in a Mouse Model of NMNAT1-Associated Retinal Degeneration.
Greenwald SH, Brown EE, Scandura MJ, Hennessey E, Farmer R, Pawlyk BS, Xiao R, Vandenberghe LH, Pierce EA.
Greenwald SH, et al. Among authors: scandura mj.
Mol Ther Methods Clin Dev. 2020 Jul 9;18:582-594. doi: 10.1016/j.omtm.2020.07.003. eCollection 2020 Sep 11.
Mol Ther Methods Clin Dev. 2020.
PMID: 32775493
Free PMC article.
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Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration.
Greenwald SH, Brown EE, Scandura MJ, Hennessey E, Farmer R, Du J, Wang Y, Pierce EA.
Greenwald SH, et al. Among authors: scandura mj.
Hum Mol Genet. 2021 May 17;30(8):644-657. doi: 10.1093/hmg/ddab070.
Hum Mol Genet. 2021.
PMID: 33709122
Free PMC article.
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